Exam Overview

• Post Name: Bio-Chemist
• Department: The Pharmaceutical Corporation - IM - Kerala Ltd
• Paper Code: 189/2015
• Date of Examination: 08-10-2015
• Conducting Authority: Kerala Public Service Commission
• Exam Mode: Offline (OMR-based)
• Total Questions: 100
• Total Marks: 100
• Duration: 1 hour 15 minutes
• Negative Marking: 0.33 marks deducted for each incorrect answer

Exam Pattern & Syllabus

The Bio-Chemist Exam consisted of multiple-choice questions (MCQs) covering General Knowledge, Current Affairs, General Science, Basic Chemistry & Biochemistry, and Subject-Specific Topics related to Pharmaceutical Sciences.

1. General Knowledge & Current Affairs

• Indian & Kerala History (Freedom Struggles, Social Reformers)
• Geography of India & Kerala
• Indian Polity & Constitution
• Economic & Social Development Policies
• Science & Technology Advancements
• Current Affairs related to Kerala, India, and the world

2. General Science

• Basics of Physics, Chemistry, and Biology
• Applications of Science in daily life
• Environmental Science and Sustainability Concepts

3. Basic Chemistry & Biochemistry

• Atomic Structure & Chemical Bonding
• Chemical Reactions & Equations
• Organic & Inorganic Chemistry Basics
• Properties of Elements & Compounds
• Acids, Bases, and Salts
• Thermodynamics & Kinetics in Chemical Reactions

4. Subject-Specific Knowledge (Biochemistry & Pharmaceutical Sciences)

This section tested candidates on biochemical concepts, molecular biology, and pharmaceutical applications.

Biochemistry Fundamentals

• Structure & Functions of Proteins, Carbohydrates, Lipids, and Nucleic Acids
• Enzyme Kinetics, Mechanism, and Inhibition
• Metabolic Pathways (Glycolysis, TCA Cycle, Electron Transport Chain)
• Vitamins & Coenzymes – Their Role in Metabolism
• Hormones – Mechanism of Action & Regulation
• Genetic Material (DNA & RNA) – Replication, Transcription, Translation
• Cell Structure & Function

Clinical Biochemistry & Laboratory Techniques

• Blood Composition & Hematology
• Urine Analysis & Biochemical Tests
• Lipid Profile, Liver Function Tests, Renal Function Tests
• Chromatography, Spectroscopy, and Electrophoresis Techniques
• Immunology & Immunochemical Techniques
• Microbiological Assays & Enzyme Assays

Pharmaceutical Biochemistry

• Drug Metabolism & Pharmacokinetics
• Role of Enzymes in Drug Action
• Biochemical Role of Medicinal Plants & Herbal Drugs
• Quality Control in Pharmaceuticals
• Ayurvedic & Traditional Medicine Biochemistry

Industrial & Applied Biochemistry

• Fermentation Technology (Production of Antibiotics, Enzymes, and Vitamins)
• Biochemical Engineering & Bioprocessing
• Recombinant DNA Technology & Genetic Engineering
• Nanobiotechnology & Drug Delivery Systems

Click the below link to download PDF format of Kerala PSC Previous Question Paper of  Bio-Chemist